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Maximal Expression of Foxl2 in Pituitary Gonadotropes Requires Ovarian Hormones

Gonadotropin-releasing hormone (GnRH) and activin regulate synthesis of FSH and ultimately fertility. Recent in vivo studies cast SMAD4 and FOXL2 as master transcriptional mediators of activin signaling that act together and independently of GnRH to regulate Fshb gene expression and female fertility...

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Detalles Bibliográficos
Autores principales: Herndon, Maria K., Nilson, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425675/
https://www.ncbi.nlm.nih.gov/pubmed/25955311
http://dx.doi.org/10.1371/journal.pone.0126527

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