A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related Transcrip...

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Detalles Bibliográficos
Autores principales: Shiwen, Xu, Stratton, Richard, Nikitorowicz-Buniak, Joanna, Ahmed-Abdi, Bahja, Ponticos, Markella, Denton, Christopher, Abraham, David, Takahashi, Ayuko, Suki, Bela, Layne, Matthew D., Lafyatis, Robert, Smith, Barbara D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425676/
https://www.ncbi.nlm.nih.gov/pubmed/25955164
http://dx.doi.org/10.1371/journal.pone.0126015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425676/
https://www.ncbi.nlm.nih.gov/pubmed/25955164
http://dx.doi.org/10.1371/journal.pone.0126015

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