An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells

BACKGROUND: Multidrug resistant cancer cells are hard to eradicate for the inefficacy of conventional anticancer drugs. Besides escaping the cytotoxic effects of chemotherapy, they also bypass the pro-immunogenic effects induced by anticancer drugs: indeed they are not well recognized by host dendri...

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Detalles Bibliográficos
Autores principales: Campia, Ivana, Buondonno, Ilaria, Castella, Barbara, Rolando, Barbara, Kopecka, Joanna, Gazzano, Elena, Ghigo, Dario, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425697/
https://www.ncbi.nlm.nih.gov/pubmed/25955018
http://dx.doi.org/10.1371/journal.pone.0126159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425697/
https://www.ncbi.nlm.nih.gov/pubmed/25955018
http://dx.doi.org/10.1371/journal.pone.0126159

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