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An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells
BACKGROUND: Multidrug resistant cancer cells are hard to eradicate for the inefficacy of conventional anticancer drugs. Besides escaping the cytotoxic effects of chemotherapy, they also bypass the pro-immunogenic effects induced by anticancer drugs: indeed they are not well recognized by host dendri...
Autores principales: | Campia, Ivana, Buondonno, Ilaria, Castella, Barbara, Rolando, Barbara, Kopecka, Joanna, Gazzano, Elena, Ghigo, Dario, Riganti, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425697/ https://www.ncbi.nlm.nih.gov/pubmed/25955018 http://dx.doi.org/10.1371/journal.pone.0126159 |
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