Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies

Genetic association studies routinely involve massive numbers of statistical tests accompanied by P-values. Whole genome sequencing technologies increased the potential number of tested variants to tens of millions. The more tests are performed, the smaller P-value is required to be deemed significa...

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Detalles Bibliográficos
Autores principales: Kuo, Chia-Ling, Vsevolozhskaya, Olga A., Zaykin, Dmitri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425705/
https://www.ncbi.nlm.nih.gov/pubmed/25955023
http://dx.doi.org/10.1371/journal.pone.0124107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425705/
https://www.ncbi.nlm.nih.gov/pubmed/25955023
http://dx.doi.org/10.1371/journal.pone.0124107

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