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Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies
Genetic association studies routinely involve massive numbers of statistical tests accompanied by P-values. Whole genome sequencing technologies increased the potential number of tested variants to tens of millions. The more tests are performed, the smaller P-value is required to be deemed significa...
Autores principales: | Kuo, Chia-Ling, Vsevolozhskaya, Olga A., Zaykin, Dmitri V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425705/ https://www.ncbi.nlm.nih.gov/pubmed/25955023 http://dx.doi.org/10.1371/journal.pone.0124107 |
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