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Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors

BACKGROUND: J591 is a monoclonal antibody that targets the external domain of the prostate-specific membrane antigen (PSMA). Besides prostate cancer cells, it also targets the neovasculature of non-prostate solid tumors. We provide an analysis of the antibody mass-dose dependency of lesion uptake an...

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Detalles Bibliográficos
Autores principales: Pandit-Taskar, Neeta, O’Donoghue, Joseph A, Divgi, Chaitanya R, Wills, Eze A, Schwartz, Lawrence, Gönen, Mithat, Smith-Jones, Peter, Bander, Neil H, Scher, Howard I, Larson, Steven M, Morris, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425739/
https://www.ncbi.nlm.nih.gov/pubmed/25984435
http://dx.doi.org/10.1186/s13550-015-0104-4