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Comparative sequence- and structure-inspired drug design for PilF protein of Neisseria meningitidis

Serogroup A of Neisseria meningitidis is the organism responsible for causing epidemic diseases in developing countries by a pilus-mediated adhesion to human brain endothelial cells. Type IV pilus assembly protein (PilF) associated with bacterial adhesion, aggregation, invasion, host cell signaling,...

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Detalles Bibliográficos
Autores principales: Mehta, Abijeet Singh, Snigdha, Kirti, Potukuchi, M Sharada, Tsonis, Panagiotis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425860/
https://www.ncbi.nlm.nih.gov/pubmed/25928839
http://dx.doi.org/10.1186/s40246-015-0027-1