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Comparative sequence- and structure-inspired drug design for PilF protein of Neisseria meningitidis
Serogroup A of Neisseria meningitidis is the organism responsible for causing epidemic diseases in developing countries by a pilus-mediated adhesion to human brain endothelial cells. Type IV pilus assembly protein (PilF) associated with bacterial adhesion, aggregation, invasion, host cell signaling,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425860/ https://www.ncbi.nlm.nih.gov/pubmed/25928839 http://dx.doi.org/10.1186/s40246-015-0027-1 |