Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells

BACKGROUND: Mycobacterium tuberculosis continues to kill more people than any other bacterium. Although its archetypal host cell is the macrophage, it also enters, and survives within, dendritic cells (DCs). By modulating the behaviour of the DC, M. tuberculosis is able to manipulate the host’s immu...

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Detalles Bibliográficos
Autores principales: Mendum, Tom A, Wu, Huihai, Kierzek, Andrzej M, Stewart, Graham R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425887/
https://www.ncbi.nlm.nih.gov/pubmed/25956932
http://dx.doi.org/10.1186/s12864-015-1569-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425887/
https://www.ncbi.nlm.nih.gov/pubmed/25956932
http://dx.doi.org/10.1186/s12864-015-1569-2

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