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Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region

INTRODUCTION: Human parthenogenetic embryonic stem cells (hpESCs) are generated from artificially activated oocytes, however, the issue of whether hpESCs have equivalent differentiation ability to human fertilized embryonic stem cells remains controversial. METHODS: hpESCs were injected into male se...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Gao, Qian, Zhao, Hong-cui, Li, Rong, Gao, Jiang-man, Ding, Ting, Bao, Si-yu, Zhao, Yue, Sun, Xiao-fang, Fan, Yong, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425892/
https://www.ncbi.nlm.nih.gov/pubmed/25879223
http://dx.doi.org/10.1186/s13287-015-0054-9