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Nonsense and missense mutation of mitochondrial ND6 gene promotes cell migration and invasion in human lung adenocarcinoma

BACKGROUND: Previous study showed that mitochondrial ND6 (mitND6) gene missense mutation resulted in NADH dehydrogenase deficiency and was associated with tumor metastasis in several mouse tumor cell lines. In the present study, we investigated the possible role of mitND6 gene nonsense and missense...

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Detalles Bibliográficos
Autores principales: Yuan, Yang, Wang, Weixing, Li, Huizhong, Yu, Yongwei, Tao, Jin, Huang, Shengdong, Zeng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425906/
https://www.ncbi.nlm.nih.gov/pubmed/25934296
http://dx.doi.org/10.1186/s12885-015-1349-z