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Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells
BACKGROUND: Cancer cells exhibit increased glycolysis for ATP production (the Warburg effect) and macromolecular biosynthesis; it is also linked with therapeutic resistance that is generally associated with compromised respiratory metabolism. Molecular mechanisms underlying radio-resistance linked t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425929/ https://www.ncbi.nlm.nih.gov/pubmed/25925410 http://dx.doi.org/10.1186/s12885-015-1368-9 |