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Precision-cut rat, mouse, and human intestinal slices as novel models for the early-onset of intestinal fibrosis

Intestinal fibrosis (IF) is a major complication of inflammatory bowel disease. IF research is limited by the lack of relevant in vitro and in vivo models. We evaluated precision-cut intestinal slices (PCIS) prepared from human, rat, and mouse intestine as ex vivo models mimicking the early-onset of...

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Detalles Bibliográficos
Autores principales: Pham, Bao Tung, van Haaften, Wouter Tobias, Oosterhuis, Dorenda, Nieken, Judith, de Graaf, Inge Anne Maria, Olinga, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425951/
https://www.ncbi.nlm.nih.gov/pubmed/25907784
http://dx.doi.org/10.14814/phy2.12323