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Protective role of female gender in programmed accelerated renal aging in the rat

The aging kidney exhibits a progressive decline in glomerular filtration rate, accompanied by inflammatory and oxidative damage. We hypothesized that accelerated, age-related progression of renal injury is ovarian hormones-dependant. To address this we used an established model of developmentally pr...

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Detalles Bibliográficos
Autores principales: Pijacka, Wioletta, Clifford, Bethan, Tilburgs, Chantal, Joles, Jaap A, Langley-Evans, Simon, McMullen, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425955/
https://www.ncbi.nlm.nih.gov/pubmed/25902787
http://dx.doi.org/10.14814/phy2.12342