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Compensatory responses of the insulin signaling pathway restore muscle glucose uptake following long-term denervation

We investigated the role of muscle activity in maintaining normal glucose homeostasis via transection of the sciatic nerve, an extreme model of disuse atrophy. Mice were killed 3, 10, 28, or 56 days after transection or sham surgery. There was no difference in muscle weight between sham and transect...

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Detalles Bibliográficos
Autores principales: Callahan, Zachary J, Oxendine, Michael, Wheatley, Joshua L, Menke, Chelsea, Cassell, Emily A, Bartos, Amanda, Geiger, Paige C, Schaeffer, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425965/
https://www.ncbi.nlm.nih.gov/pubmed/25896980
http://dx.doi.org/10.14814/phy2.12359