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mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance

Diacylglycerol kinase (DGK) isoforms regulate signal transduction and lipid metabolism. DGKδ deficiency leads to hyperglycemia, peripheral insulin resistance, and metabolic inflexibility. Thus, dysregulation of other DGK isoforms may play a role in metabolic dysfunction. We investigated DGK isoform...

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Detalles Bibliográficos
Autores principales: Mannerås-Holm, Louise, Kirchner, Henriette, Björnholm, Marie, Chibalin, Alexander V, Zierath, Juleen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425976/
https://www.ncbi.nlm.nih.gov/pubmed/25847921
http://dx.doi.org/10.14814/phy2.12372