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Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice

Transient nutrient restriction in the 3 weeks between birth and weaning (producing “crowded litter” or CL mice) leads to a significant increase in lifespan and is associated with permanent changes in energy homeostasis, leptin, and insulin sensitivity. Here, we show this brief period of early food r...

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Detalles Bibliográficos
Autores principales: Sadagurski, Marianna, Landeryou, Taylor, Cady, Gillian, Bartke, Andrzej, Bernal-Mizrachi, Ernesto, Miller, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425981/
https://www.ncbi.nlm.nih.gov/pubmed/25907790
http://dx.doi.org/10.14814/phy2.12379