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Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice
Transient nutrient restriction in the 3 weeks between birth and weaning (producing “crowded litter” or CL mice) leads to a significant increase in lifespan and is associated with permanent changes in energy homeostasis, leptin, and insulin sensitivity. Here, we show this brief period of early food r...
Autores principales: | Sadagurski, Marianna, Landeryou, Taylor, Cady, Gillian, Bartke, Andrzej, Bernal-Mizrachi, Ernesto, Miller, Richard A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425981/ https://www.ncbi.nlm.nih.gov/pubmed/25907790 http://dx.doi.org/10.14814/phy2.12379 |
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