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Disease course in mdx:utrophin(+/−) mice: comparison of three mouse models of Duchenne muscular dystrophy

The mdx mouse model of Duchenne muscular dystrophy (DMD) is used to study disease mechanisms and potential treatments, but its pathology is less severe than DMD patients. Other mouse models were developed to more closely mimic the human disease based on knowledge that upregulation of utrophin has a...

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Detalles Bibliográficos
Autores principales: McDonald, Abby A, Hebert, Sadie L, Kunz, Matthew D, Ralles, Steven J, McLoon, Linda K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425985/
https://www.ncbi.nlm.nih.gov/pubmed/25921779
http://dx.doi.org/10.14814/phy2.12391