Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants

Brc1, which was first identified as a high-copy, allele-specific suppressor of a mutation impairing the Smc5-Smc6 holocomplex in Schizosaccharomyces pombe, protects genome integrity during normal DNA replication and when cells are exposed to toxic compounds that stall or collapse replication forks....

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Detalles Bibliográficos
Autores principales: Sánchez, Arancha, Roguev, Assen, Krogan, Nevan J., Russell, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426379/
https://www.ncbi.nlm.nih.gov/pubmed/25795664
http://dx.doi.org/10.1534/g3.115.017251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426379/
https://www.ncbi.nlm.nih.gov/pubmed/25795664
http://dx.doi.org/10.1534/g3.115.017251

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