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Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants

Brc1, which was first identified as a high-copy, allele-specific suppressor of a mutation impairing the Smc5-Smc6 holocomplex in Schizosaccharomyces pombe, protects genome integrity during normal DNA replication and when cells are exposed to toxic compounds that stall or collapse replication forks....

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Detalles Bibliográficos
Autores principales:	Sánchez, Arancha, Roguev, Assen, Krogan, Nevan J., Russell, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426379/ https://www.ncbi.nlm.nih.gov/pubmed/25795664 http://dx.doi.org/10.1534/g3.115.017251

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