Leveraging DNA Damage Response Signaling to Identify Yeast Genes Controlling Genome Stability

Oncogenesis frequently is accompanied by rampant genome instability, which fuels genetic heterogeneity and resistance to targeted cancer therapy. We have developed an approach that allows precise, quantitative measurement of genome instability in high-throughput format in the Saccharomyces cerevisia...

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Detalles Bibliográficos
Autores principales: Hendry, Jason A., Tan, Guihong, Ou, Jiongwen, Boone, Charles, Brown, Grant W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Mutant Screen Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426383/
https://www.ncbi.nlm.nih.gov/pubmed/25721128
http://dx.doi.org/10.1534/g3.115.016576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426383/
https://www.ncbi.nlm.nih.gov/pubmed/25721128
http://dx.doi.org/10.1534/g3.115.016576

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