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Leveraging DNA Damage Response Signaling to Identify Yeast Genes Controlling Genome Stability
Oncogenesis frequently is accompanied by rampant genome instability, which fuels genetic heterogeneity and resistance to targeted cancer therapy. We have developed an approach that allows precise, quantitative measurement of genome instability in high-throughput format in the Saccharomyces cerevisia...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426383/ https://www.ncbi.nlm.nih.gov/pubmed/25721128 http://dx.doi.org/10.1534/g3.115.016576 |