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Hypermethylated Epidermal growth factor receptor (EGFR) promoter is associated with gastric cancer

Epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinases ErbB family and it is found to be overexpressed in gastric cancer. However, the mechanism of the regulation of the EGFR expression is still unknown. We used the Sequenom EpiTYPER assay to detect the methylation stat...

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Detalles Bibliográficos
Autores principales: Weng, Xiaoling, Zhang, Hong, Ye, Junyi, Kan, Mengyuan, Liu, Fatao, Wang, Ting, Deng, Jiaying, Tan, Yanfang, He, Lin, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426697/
https://www.ncbi.nlm.nih.gov/pubmed/25959250
http://dx.doi.org/10.1038/srep10154