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High Maternal Serum Estradiol Levels Induce Dyslipidemia in Human Newborns via a Hepatic HMGCR Estrogen Response Element

While the intrauterine environment is essential for the health of offspring, the impact of high maternal serum estradiol (E(2)) on lipid metabolism in offspring and the mechanisms are unknown. We found that ovarian stimulation (OS) could result in high E(2) levels in women throughout pregnancy. Stri...

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Detalles Bibliográficos
Autores principales: Meng, Ye, Lv, Ping-Ping, Ding, Guo-Lian, Yu, Tian-Tian, Liu, Ye, Shen, Yan, Hu, Xiao-Ling, Lin, Xian-Hua, Tian, Shen, Lv, Min, Song, Yang, Guo, Meng-Xi, Ke, Zhang-Hong, Xu, Hong, Sheng, Jian-Zhong, Shi, Feng-Tao, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426719/
https://www.ncbi.nlm.nih.gov/pubmed/25961186
http://dx.doi.org/10.1038/srep10086