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The dichotomy of memantine treatment for ischemic stroke: dose-dependent protective and detrimental effects
Excitotoxicity is a major contributor to cell death during the acute phase of ischemic stroke but aggressive pharmacological targeting of excitotoxicity has failed clinically. Here we investigated whether pretreatment with low doses of memantine, within the range currently used and well tolerated fo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426739/ https://www.ncbi.nlm.nih.gov/pubmed/25407270 http://dx.doi.org/10.1038/jcbfm.2014.188 |