Genome-wide Computational Analysis Reveals Cardiomyocyte-specific Transcriptional Cis-regulatory Motifs That Enable Efficient Cardiac Gene Therapy

Gene therapy is a promising emerging therapeutic modality for the treatment of cardiovascular diseases and hereditary diseases that afflict the heart. Hence, there is a need to develop robust cardiac-specific expression modules that allow for stable expression of the gene of interest in cardiomyocyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Rincon, Melvin Y, Sarcar, Shilpita, Danso-Abeam, Dina, Keyaerts, Marleen, Matrai, Janka, Samara-Kuko, Ermira, Acosta-Sanchez, Abel, Athanasopoulos, Takis, Dickson, George, Lahoutte, Tony, De Bleser, Pieter, VandenDriessche, Thierry, Chuah, Marinee K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426801/
https://www.ncbi.nlm.nih.gov/pubmed/25195597
http://dx.doi.org/10.1038/mt.2014.178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426801/
https://www.ncbi.nlm.nih.gov/pubmed/25195597
http://dx.doi.org/10.1038/mt.2014.178

Ejemplares similares