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Coupling between the Circadian Clock and Cell Cycle Oscillators: Implication for Healthy Cells and Malignant Growth

Uncontrolled cell proliferation is one of the key features leading to cancer. Seminal works in chronobiology have revealed that disruption of the circadian timing system in mice, either by surgical, genetic, or environmental manipulation, increased tumor development. In humans, shift work is a risk...

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Detalles Bibliográficos
Autores principales: Feillet, Celine, van der Horst, Gijsbertus T. J., Levi, Francis, Rand, David A., Delaunay, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426821/
https://www.ncbi.nlm.nih.gov/pubmed/26029155
http://dx.doi.org/10.3389/fneur.2015.00096