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MADGiC: a model-based approach for identifying driver genes in cancer

Motivation: Identifying and prioritizing somatic mutations is an important and challenging area of cancer research that can provide new insights into gene function as well as new targets for drug development. Most methods for prioritizing mutations rely primarily on frequency-based criteria, where a...

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Detalles Bibliográficos
Autores principales: Korthauer, Keegan D., Kendziorski, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426832/
https://www.ncbi.nlm.nih.gov/pubmed/25573922
http://dx.doi.org/10.1093/bioinformatics/btu858