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Combining tree-based and dynamical systems for the inference of gene regulatory networks

Motivation: Reconstructing the topology of gene regulatory networks (GRNs) from time series of gene expression data remains an important open problem in computational systems biology. Existing GRN inference algorithms face one of two limitations: model-free methods are scalable but suffer from a lac...

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Detalles Bibliográficos
Autores principales: Huynh-Thu, Vân Anh, Sanguinetti, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426834/
https://www.ncbi.nlm.nih.gov/pubmed/25573916
http://dx.doi.org/10.1093/bioinformatics/btu863