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Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
The energy required to fuse synaptic vesicles with the plasma membrane (‘activation energy’) is considered a major determinant in synaptic efficacy. From reaction rate theory, we predict that a class of modulations exists, which utilize linear modulation of the energy barrier for fusion to achieve s...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426983/ https://www.ncbi.nlm.nih.gov/pubmed/25871846 http://dx.doi.org/10.7554/eLife.05531 |