Muramyl Dipeptide Enhances Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption through Increased RANKL Expression in Stromal Cells

Lipopolysaccharide (LPS) is bacterial cell wall component capable of inducing osteoclast formation and pathological bone resorption. Muramyl dipeptide (MDP), the minimal essential structural unit responsible for the immunological activity of peptidoglycans, is ubiquitously expressed by bacterium. In...

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Detalles Bibliográficos
Autores principales: Ishida, Masahiko, Kitaura, Hideki, Kimura, Keisuke, Sugisawa, Haruki, Aonuma, Tomo, Takada, Haruhiko, Takano-Yamamoto, Teruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427123/
https://www.ncbi.nlm.nih.gov/pubmed/26000311
http://dx.doi.org/10.1155/2015/132765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427123/
https://www.ncbi.nlm.nih.gov/pubmed/26000311
http://dx.doi.org/10.1155/2015/132765

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