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The structure of tubulin-binding cofactor A from Leishmania major infers a mode of association during the early stages of microtubule assembly

Tubulin-binding cofactor A (TBCA) participates in microtubule formation, a key process in eukaryotic biology to create the cytoskeleton. There is little information on how TBCA might interact with β-tubulin en route to microtubule biogenesis. To address this, the protozoan Leishmania major was targe...

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Detalles Bibliográficos
Autores principales: Barrack, Keri L., Fyfe, Paul K., Hunter, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427162/
https://www.ncbi.nlm.nih.gov/pubmed/25945706
http://dx.doi.org/10.1107/S2053230X15000990