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Structures of the Middle East respiratory syndrome coronavirus 3C‐like protease reveal insights into substrate specificity

Middle East respiratory syndrome coronavirus (MERS‐CoV) is a highly pathogenic virus that causes severe respiratory illness accompanied by multi‐organ dysfunction, resulting in a case fatality rate of approximately 40%. As found in other coronaviruses, the majority of the positive‐stranded RNA MERS‐...

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Detalles Bibliográficos
Autores principales: Needle, Danielle, Lountos, George T., Waugh, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427198/
https://www.ncbi.nlm.nih.gov/pubmed/25945576
http://dx.doi.org/10.1107/S1399004715003521