Discovering New Medicines Targeting Helicases: Challenges and Recent Progress

Helicases are ubiquitous motor proteins that separate and/or rearrange nucleic acid duplexes in reactions fueled by adenosine triphosphate (ATP) hydrolysis. Helicases encoded by bacteria, viruses, and human cells are widely studied targets for new antiviral, antibiotic, and anticancer drugs. This re...

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Detalles Bibliográficos
Autores principales: Shadrick, William R., Ndjomou, Jean, Kolli, Rajesh, Mukherjee, Sourav, Hanson, Alicia M., Frick, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Laboratory Automation and Screening. Published by Elsevier Inc. 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427233/
https://www.ncbi.nlm.nih.gov/pubmed/23536547
http://dx.doi.org/10.1177/1087057113482586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427233/
https://www.ncbi.nlm.nih.gov/pubmed/23536547
http://dx.doi.org/10.1177/1087057113482586

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