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Discovering New Medicines Targeting Helicases: Challenges and Recent Progress
Helicases are ubiquitous motor proteins that separate and/or rearrange nucleic acid duplexes in reactions fueled by adenosine triphosphate (ATP) hydrolysis. Helicases encoded by bacteria, viruses, and human cells are widely studied targets for new antiviral, antibiotic, and anticancer drugs. This re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Society for Laboratory Automation and Screening. Published by Elsevier Inc.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427233/ https://www.ncbi.nlm.nih.gov/pubmed/23536547 http://dx.doi.org/10.1177/1087057113482586 |