Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters

There is an urgent need for improved models for cardiotoxicity testing. Here we propose acoustic sensing applied to beating human cardiomyocyte clusters for non-invasive, surrogate measuring of the QT interval and other characteristics of the contractile machinery. In experiments with the acoustic m...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunze, Angelika, Steel, Daniella, Dahlenborg, Kerstin, Sartipy, Peter, Svedhem, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427273/
https://www.ncbi.nlm.nih.gov/pubmed/25961711
http://dx.doi.org/10.1371/journal.pone.0125540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427273/
https://www.ncbi.nlm.nih.gov/pubmed/25961711
http://dx.doi.org/10.1371/journal.pone.0125540

Ejemplares similares