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A Newton Cooperative Genetic Algorithm Method for In Silico Optimization of Metabolic Pathway Production

This paper presents an in silico optimization method of metabolic pathway production. The metabolic pathway can be represented by a mathematical model known as the generalized mass action model, which leads to a complex nonlinear equations system. The optimization process becomes difficult when stea...

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Detalles Bibliográficos
Autores principales: Ismail, Mohd Arfian, Deris, Safaai, Mohamad, Mohd Saberi, Abdullah, Afnizanfaizal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427276/
https://www.ncbi.nlm.nih.gov/pubmed/25961295
http://dx.doi.org/10.1371/journal.pone.0126199