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A Newton Cooperative Genetic Algorithm Method for In Silico Optimization of Metabolic Pathway Production
This paper presents an in silico optimization method of metabolic pathway production. The metabolic pathway can be represented by a mathematical model known as the generalized mass action model, which leads to a complex nonlinear equations system. The optimization process becomes difficult when stea...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427276/ https://www.ncbi.nlm.nih.gov/pubmed/25961295 http://dx.doi.org/10.1371/journal.pone.0126199 |