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Dendritic-Tumor Fusion Cells Derived Heat Shock Protein70-Peptide Complex Has Enhanced Immunogenicity

Tumor-derived heat shock protein70-peptide complexes (HSP70.PC-Tu) have shown great promise in tumor immunotherapy due to numerous advantages. However, large-scale phase III clinical trials showed that the limited immunogenicity remained to be enhanced. In previous research, we demonstrated that hea...

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Detalles Bibliográficos
Autores principales: Zhang, Yunfei, Zhang, Yong, Chen, Jun, Liu, Yunyan, Luo, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427282/
https://www.ncbi.nlm.nih.gov/pubmed/25961716
http://dx.doi.org/10.1371/journal.pone.0126075