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A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition

Bacterial efflux pumps are active transport proteins responsible for resistance to selected biocides and antibiotics. It has been shown that production of efflux pumps is up-regulated in a number of highly pathogenic bacteria, including methicillin resistant Staphylococcus aureus. Thus, the identifi...

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Detalles Bibliográficos
Autores principales: Brown, Adam R., Ettefagh, Keivan A., Todd, Daniel, Cole, Patrick S., Egan, Joseph M., Foil, Daniel H., Graf, Tyler N., Schindler, Bryan D., Kaatz, Glenn W., Cech, Nadja B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427306/
https://www.ncbi.nlm.nih.gov/pubmed/25961825
http://dx.doi.org/10.1371/journal.pone.0124814