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A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition
Bacterial efflux pumps are active transport proteins responsible for resistance to selected biocides and antibiotics. It has been shown that production of efflux pumps is up-regulated in a number of highly pathogenic bacteria, including methicillin resistant Staphylococcus aureus. Thus, the identifi...
Autores principales: | Brown, Adam R., Ettefagh, Keivan A., Todd, Daniel, Cole, Patrick S., Egan, Joseph M., Foil, Daniel H., Graf, Tyler N., Schindler, Bryan D., Kaatz, Glenn W., Cech, Nadja B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427306/ https://www.ncbi.nlm.nih.gov/pubmed/25961825 http://dx.doi.org/10.1371/journal.pone.0124814 |
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