High Glucose Induces Bone Marrow-Derived Mesenchymal Stem Cell Senescence by Upregulating Autophagy

Hyperglycemia was reported to cause bone marrow hematopoietic niche dysfunction, and high glucose (HG) in the cultured medium induces MSC senescence. The underlying mechanism is unclear. Here, we investigated the role of HG-induced autophagy in bone-marrow-derived mesenchymal stem cell (BMSC) senesc...

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Detalles Bibliográficos
Autores principales: Chang, Tzu-Ching, Hsu, Min-Fen, Wu, Kenneth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427318/
https://www.ncbi.nlm.nih.gov/pubmed/25961745
http://dx.doi.org/10.1371/journal.pone.0126537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427318/
https://www.ncbi.nlm.nih.gov/pubmed/25961745
http://dx.doi.org/10.1371/journal.pone.0126537

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