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Trichostatin A Rescues the Disrupted Imprinting Induced by Somatic Cell Nuclear Transfer in Pigs

Imprinting disorders induced by somatic cell nuclear transfer (SCNT) usually lead to the abnormalities of cloned animals and low cloning efficiency. Histone deacetylase inhibitors have been shown to improve gene expression, genomic methylation reprogramming and the development of cloned embryos, how...

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Detalles Bibliográficos
Autores principales: Huan, Yanjun, Zhu, Jiang, Huang, Bo, Mu, Yanshuang, Kong, Qingran, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427324/
https://www.ncbi.nlm.nih.gov/pubmed/25962071
http://dx.doi.org/10.1371/journal.pone.0126607