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Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer

Biomarkers and novel therapeutic targets are urgently needed in colorectal cancer (CRC). The pseudo tyrosine kinase receptor 7 (PTK7) is involved in planar cell polarity and it is deregulated in various malignancies, including CRC. Yet, little is known about its protein expression in human CRC, or a...

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Detalles Bibliográficos
Autores principales: Lhoumeau, Anne-Catherine, Martinez, Sébastien, Boher, Jean-Marie, Monges, Geneviève, Castellano, Rémy, Goubard, Armelle, Doremus, Marie, Poizat, Flora, Lelong, Bernard, de Chaisemartin, Cécile, Bardin, Florence, Viens, Patrice, Raoul, Jean-Luc, Prebet, Thomas, Aurrand-Lions, Michel, Borg, Jean-Paul, Gonçalves, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427440/
https://www.ncbi.nlm.nih.gov/pubmed/25962058
http://dx.doi.org/10.1371/journal.pone.0123768