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TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post‐Mortem Temporal Cortices

Triggering receptor expressed by myeloid cells 2 (TREM2), a member of the immunoglobulin superfamily, has anti‐inflammatory phagocytic function in myeloid cells. Several studies have shown that TREM 2 gene variant rs75932628‐T increased the risks for Alzheimer's disease (AD), Parkinson's d...

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Detalles Bibliográficos
Autores principales: Lue, Lih‐Fen, Schmitz, Christopher T., Serrano, Geidy, Sue, Lucia I., Beach, Thomas G., Walker, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427527/
https://www.ncbi.nlm.nih.gov/pubmed/25186950
http://dx.doi.org/10.1111/bpa.12190