Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies

BACKGROUND: Inadequate intrapleural drug concentrations caused by poor penetration of systemic antibiotics into the pleural cavity is a major cause of treatment failure in empyema. Herein, we describe a novel antibiotic-eluting pigtail catheter coated with electrospun nanofibers used for the sustain...

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Detalles Bibliográficos
Autores principales: Chao, Yin-Kai, Lee, Cheng-Hung, Liu, Kuo-Sheng, Wang, Yi-Chuan, Wang, Chih-Wei, Liu, Shih-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427606/
https://www.ncbi.nlm.nih.gov/pubmed/26005344
http://dx.doi.org/10.2147/IJN.S82228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427606/
https://www.ncbi.nlm.nih.gov/pubmed/26005344
http://dx.doi.org/10.2147/IJN.S82228

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