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Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes

Oxidative stress contributes to pathology associated with inflammatory brain disorders and therapies that upregulate antioxidant pathways may be neuroprotective in diseases such as multiple sclerosis. Dimethyl fumarate, a small molecule therapeutic for multiple sclerosis, activates cellular antioxid...

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Detalles Bibliográficos
Autores principales: Huang, He, Taraboletti, Alexandra, Shriver, Leah P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427661/
https://www.ncbi.nlm.nih.gov/pubmed/25967672
http://dx.doi.org/10.1016/j.redox.2015.04.011