Synthesis and biological evaluation of some novel 1-substituted fentanyl analogs in Swiss albino mice

Fentanyl [N-(1-phenethyl-4-piperidinyl)propionanilide] is a potent opioid analgesic agent, but a has narrow therapeutic index. We reported earlier on the synthesis and bioefficacy of fentanyl and its 1-substituted analogs (1–4) in mice. Here we report the synthesis and biological evaluation of four...

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Detalles Bibliográficos
Autores principales: Yadav, Shiv Kumar, Maurya, Chandra Kant, Gupta, Pradeep Kumar, Jain, Ajai Kumar, Ganesan, Kumaran, Bhattacharya, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427721/
https://www.ncbi.nlm.nih.gov/pubmed/26109885
http://dx.doi.org/10.2478/intox-2014-0013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427721/
https://www.ncbi.nlm.nih.gov/pubmed/26109885
http://dx.doi.org/10.2478/intox-2014-0013

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