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Synthesis and biological evaluation of some novel 1-substituted fentanyl analogs in Swiss albino mice
Fentanyl [N-(1-phenethyl-4-piperidinyl)propionanilide] is a potent opioid analgesic agent, but a has narrow therapeutic index. We reported earlier on the synthesis and bioefficacy of fentanyl and its 1-substituted analogs (1–4) in mice. Here we report the synthesis and biological evaluation of four...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Slovak Toxicology Society SETOX
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427721/ https://www.ncbi.nlm.nih.gov/pubmed/26109885 http://dx.doi.org/10.2478/intox-2014-0013 |